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We are independently developed TechnologyTV website. However we are not a part of or are not legally affiliated with any product vendor listed on this website. Any company names, brand names, trademarks, logos, product and services mentioned on this website belong to their respective owners. We are not responsible for any miscommunication or product price that this site, its content, advertising or promotion links to products we review or cover in articles.The search for a safe, clean and effective replacement for organophosphorus nerve agents such as Sarin is highly motivated by the global danger these chemical warfare agents pose to the thousands of troops and civilians who use these toxic poisons in the course of their daily duties. This research program, stemming from our prior work with the use of chiral, nonracemic aspirin (R/S) as a chiral catalyst to enhance the transesterification of organophosphorous nerve agents, will apply the same principles to create a “chiral catalyst” for the synthesis of organophosphorous compounds and their derivatives. The long-term goal of this project is to develop a safe and effective agent to catalyze a safer, more efficient synthesis of organophosphorous compounds and derivatives that can be easily stored and readily used in field- and non-field applications. The specific aims of this project are to: (1) Create and evaluate a novel chiral catalyst based on oxa- 18-crown-6-ether and molecularly imprinted (MIP) polymer. The goal of this portion of the work is to develop a highly selective, moderately enantioselective chiral catalyst. (2) Evaluate the effectiveness of the catalyst in the asymmetric synthesis of chiral organophosphorus nerve agents. (3) Evaluate the kinetics and mechanism of the proposed cataly

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