Mach3 2010 Screenset

Mach3 2010 Screenset
Mach 3 2010 Screenset
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The influence of sleep on perceptual changes due to visual adaptation.
Recent work has shown that retinal adaptation is greatly reduced if the adapting stimulus and test stimulus are presented in different temporal sequences, suggesting that sleep may weaken retinal adaptation by interfering with the operation of visual adaptation mechanisms. Using a design similar to that used by Olszewski (1976) to test the role of sleep in the production of categorical perception, we found that subjects adapt better to a staircase when tested after a 30 s period of wakefulness than when tested after a 30 s period of sleep. This result, while providing only indirect evidence, suggests that sleep may weaken the operation of visual adaptation mechanisms in the retina and cortex.Effects of loss of tryptophan on protein synthesis in anterior pituitary cells in culture.
Male and female rats were either killed directly or cultured for 24 h. They were then implanted with bilateral adrenalectomy (A) and cannula in the jugular vein for the implantation of cannula, and were infused with a Ringer’s solution (B) or Ringer’s solution containing 6.7 mM L-tryptophan (A+D). Protein syntheses in the anterior pituitaries were measured by [3H]leucine incorporation. After 24 h culture, a suspension of tryptophan-deficient anterior pituitaries was prepared from the rat given 1.3 mM L-tryptophan (A-D) and from that given 6.7 mM L-tryptophan (A+D). The incorporation of [3H]leucine into the protein in both control and tryptophan-deficient pituitaries was significantly reduced after 24 h culture. Furthermore, the percentage of inhibition was greater in the culture media than in the gland. The difference in percentage of inhibition was more evident in the medium of the rats with 6.7 mM L-tryptophan. These results indicate that a more rapid and marked depletion of tryptophan occurs in the medium of the rat after 24 h culture. These data suggest that the mechanisms of proteolysis in the anterior pituitary are more active in the presence of tryptophan.Image copyright Reuters

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